College of Engineering
Biochemistry and Molecular Biology
Education/Degree B.S. Columbia University, NY M.S. University of Pennsylvania, PA Ph.D. University of Pennsylvania, PA
Our laboratory is focused on understanding the signaling and regulatory mechanisms that are altered in diseases, such as obesity, Alzheimer’s disease and cancer. My group develops and applies metabolic engineering, bioinformatics, and systems biology approaches in combination with biochemical, biophysical, and molecular biology measurements and animal studies to identify targets and disease biomarkers. We are also developing polymeric-based drug delivery and tissue engineering platforms to modulate these pathways for treating these diseases.
Role of ER stress in diseases (cancer and AD)
Use of crispr to reduce stem cell heterogeneity
Regenerative medicine and tissue engineering
Metabolic Engineering and Systems Biology